In a review of clinical trials internationally between 1994 and 2017, Chmieliauskaite and an international research team found that many of the participants may have had an underlying condition that could have explained their BMS symptoms. These symptoms may However, it may National Institute of Dental and Craniofacial Research. ScienceDaily. Burning mouth Chronic Orofacial Pain: Burning Mouth Syndrome and Other Neuropathic Disorders. Burning mouth syndrome (BMS) is an uncomfortable condition that creates chronic pain. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. For example, Do not take a double dose to make up for a missed one. Other details regarding symptoms include the following. Diltiazem controls high blood pressure and chest pain (angina) but does not cure them. Select a condition to view a list of medication options. contain citric acid. come and go, increase gradually as the day wears on, or be constant. Some people with burning mouth syndrome find it helpful to This medication is also available in an injectable form to be given directly into a vein (IV) by a healthcare professional. Ask your pharmacist if you should take diltiazem with or without food, because instructions may vary with each product. Take diltiazem at around the same time(s) every day. Concomitant use of diltiazem with beta-blockers or digitalis may result in additive effects on cardiac conduction. American Academy of Family Physicians, Familydoctor.org. These side effects may go away during treatment as your body adjusts to the medicine. Clipboard, Search History, and several other advanced features are temporarily unavailable. ANSWER: Before you try any treatments, I recommend you first get a thorough evaluation from a health care provider who is familiar with burning mouth syndrome. Any type of chronic pain can lead to anxiety which is known to cause sleeping problems. Last reviewed by a Cleveland Clinic medical professional on 06/26/2022. New Findings on Chronic Pain Syndrome in the Mouth, CCPA/CPRA: Do Not Sell or Share My Information. Yeast infections in the mouth, also known as oral thrush, can . Other medical conditions that can be related to burning mouth symptoms include: An estimated 1% of the adult population is affected. All rights reserved. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Learn How Genetics Make Some Fans of Fear, Dr. Whyte's Book: Take Control of Your Cancer Risk, How Breast Cancer Changed My Life and Me, Health News and Information, Delivered to Your Inbox. Doctors think the cause could be damage to nerves that control taste or pain. WebDiltiazem hydrochloride extended-release tablets may cause abnormally slow heart rates or second- or third-degree AV block. Some people have pain every day. Have you asked your doctor about Sjogren's? You should go to your primary care doctor in the next few weeks. WebDiltiazem is in a class of medications called calcium-channel blockers. Most studies have found that oral burning is frequently accompanied by other symptoms, including dry mouth and altered taste.5 Alterations in taste occur in as many as two thirds of patients and often include complaints of persistent tastes (bitter, metallic, or both) or changes in the intensity of taste perception. your health care provider has found an underlying cause of your discomfort. Clin Neurophysiol. An approach to managing painful chronic conditions called cognitive behavioral therapy can be useful for people with burning mouth syndrome. Oral health problems cause one-third of all BMS cases. Know the Reasons & Fall Asleep Faster. Materials provided by Case Western Reserve University. ", Pain Management Research Institute: "Burning Mouth/Tongue Syndrome (Glossodynia/Glossopyrosis).". He or she will examine your mouth and possibly order some tests to evaluate for reversible causes of mouth pain and develop an appropriate treatment plan. Effectively treating primary burning mouth syndrome is more complicated. WebBurning mouth syndrome and drugs with ingredients of melatonin (1 reports) Alternative drugs to, pros and cons of Melatonin: Melatonin (43,043 reports) Common Melatonin side effects: Fatigue (feeling of tiredness): 3,807 reports Headache (pain in head): 2,371 reports Drug ineffective: 2,366 reports Diarrhea: 2,362 reports This condition's etiopathogenesis is still unknown, consequently, BMS management is very challenging. WebDiltiazem is a negative inotrope and can cause decreased systolic function and heart failure. There may not be a way to prevent BMS. Online ahead of print. 2012 Jan;123(1):71-7. doi: 10.1016/j.clinph.2011.07.054. The usual dose range of oral diltiazem for controlling chest pain is 120 to 480 mg daily. Your doctor will adjust the dose and frequency of diltiazem to your needs. The dose may be increased slowly over time until treatment goals are achieved. burning mouth syndrome. The pressure on the teeth may increase the burning feeling. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Take a quiz to find out if you have burning mouth syndrome. BMS is challenging to diagnose. Continue to take diltiazem even if you feel well. Basso MA, Strecker RE, Evinger C. Midbrain 6-hydroxy-dopamine lesions modulate blink reflex excitability. occur anywhere in the mouth. Check with your doctor immediately if any of the following side effects occur while taking diltiazem: More common Body aches or pain congestion cough dryness or 2005 - 2023 WebMD LLC, an Internet Brands company. The American Academy of Oral Medicine. Cleveland Clinic is a non-profit academic medical center. Burning mouth syndrome You may need to try several treatment methods before finding one or a combination that helps reduce your mouth discomfort. Apkarian AV, Bushnell MC, Treede RD, Zubieta JK. You may need to switch medications to find the best one for you. This situation not only adds to the health care burden of these complaints but also has a significant emotional impact on patients, who are sometimes suspected of imagining or exaggerating their symptoms. 2022 Jan;17(1):399-406. doi: 10.1016/j.jds.2021.08.010. tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Who should not take Diltiazem 24HR ER (CD)? 2017 Jun;37(7):627-647. doi: 10.1177/0333102417694883. Three months with no signs of burning (side of tongue) but it came back. Your doctor may give you a different medication to take when you have chest pain. Diltiazem controls high blood pressure and chest pain (angina) but does not cure them. It may take up to 2 weeks before you feel the full benefit of diltiazem. Continue to take diltiazem even if you feel well. The main symptoms of burning mouth syndrome include the following. AHFS Patient Medication Information. It feels different for each person. There, the doctor will rule out other causes of your pain. This content is owned by the AAFP. Ozasa K, Noma N, Young A, Korczeniewska OA, Eliav E, Imamura Y. J Dent Sci. if you are having surgery, including dental surgery, tell your doctor or dentist that you are taking diltiazem. Diltiazem is also sometimes used to treat certain types of arrhythmias (abnormal heart rhythms). Tait RC, Ferguson M, Herndon CM. All rights reserved. Oral yeast infection, or thrush. Depending on the cause of your burning mouth syndrome, the doctor may suggest one or more of these treatments: You can do a few things that may help your symptoms as well: Burning mouth syndrome is a chronic pain condition and can affect your quality of life. You also may want to try over-the-counter products intended worse. This branded product is no longer on the market. What special precautions should I follow? It also increases the supply of blood and oxygen to the heart. Yes. The burning sensation often occurs in more than one oral site, with the anterior two thirds of the tongue, the anterior hard palate and the mucosa of the lower lip most frequently involved.5 Facial skin is not usually affected. Try our AI assistant here. Most women with BMS are super tasters whove since lost some of their taste sensation. First degree AV block and sinus bradycardia occurred more frequently with higher doses. Burning mouth syndrome. He currently practices as a hospitalist at Newton Wellesley Hospital. Topical capsaicin has been used as a desensitizing agent in patients with burning mouth syndrome.31 However, capsaicin may not be palatable or useful in many patients. If you have symptoms, see your dentist first. Silvestre FJ, Silvestre-Rangil J, Lpez-Jornet P. Chin J Dent Res. Although not all of these side effects may occur, if they do occur they may need medical attention. Other dosage forms: Along with its needed effects, diltiazem may cause some unwanted effects. BMS often starts seemingly out of nowhere. Mol Pain 2010;6:2744. Burning mouth syndrome (BMS) causes burning or uncomfortable feelings in the oral cavity without any obvious injuries. Merck Manual Professional Version. It may take many doctor visits to diagnose the condition. A bitter or metallic taste often happens along with the burning feeling. You may be a: Women are more likely than men to be super tasters. O 0. Epub 2022 Aug 26. Swallow the extended-release capsules and tablets whole; do not chew or crush them. Check with your doctor immediately if any of the following side effects occur while taking diltiazem: Some side effects of diltiazem may occur that usually do not need medical attention. prevention of anginal chest pain associated with coronary artery disease, ventricular rate control in atrial fibrillation, prevention of anginal pain associated with vasospastic angina, supraventricular arrhythmias, a type of abnormal heart rhythm, fluid retention in the legs, feet, arms or hands, inflammation of the tissue lining the sinuses, atrioventricular block, a type of slow heart rhythm disorder, a type of blood disorder where the red blood cells burst called hemolytic anemia, extrapyramidal disease, a type of movement disorder, a disease with shrinking and weaker muscles called myopathy, allergic reaction causing inflammation of blood vessels, erythema multiforme, a type of allergic skin reaction, a skin disorder with blistering and peeling skin called toxic epidermal necrolysis, a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome, a type of allergic reaction called angioedema, a type of skin disorder called acute generalized exanthematous pustulosis, small reddish-purplish pin-point sized spots on skin, a type of drug-related rash called lichenoid dermatitis. Still, that doesnt mean these treatments cant provide relief. If not, there's no known cure for burning mouth syndrome, but there are ways to ease and control your symptoms. is a persistent feeling of burning in the mouth that is not due to mouth Unable to load your collection due to an error, Unable to load your delegates due to an error. Are there any at-home treatments that will make it less uncomfortable? MeSH Most patients with the disorder report an increase in pain intensity from morning to night, decreased pain with eating, oral dryness that waxes and wanes with the burning, and the frequent presence of taste disturbances.8 Even when a patient reports typical features of burning mouth syndrome, other potential causes should be ruled out (Table 1). But you can lessen the symptoms by avoiding anything that irritates your mouth, including: Also, make sure your diet contains enough vitamin B12, folate and iron. If you experience mouth pain and taste changes on a near daily basis, report this to your primary care physician and dentist. Other people also develop BMS in those cases, they usually have another condition called geographic tongue. Your doctor may give you a different medication to take when you have chest pain. Hypotension . Epub 2021 Sep 2. Burning mouth syndrome: A review on its diagnostic and therapeutic approach. Webdry mouth itching hair loss drowsiness memory loss hallucinations fainting muscle tremors taste impairment abnormal manner of walking small reddish-purplish pin-point sized spots Sometimes, burning mouth syndrome results from another health event or condition. What special dietary instructions should I follow? It also can cause you to experience a bitter or amlodipine, lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide, propranolol, spironolactone. I also use clonazepam , 0.5 mg melted on my tongue as needed. An error occurred, please try again later. Recent studies have pointed to dysfunction of several cranial nerves associated with taste sensation as a possible cause of burning mouth syndrome. WebMD does not provide medical advice, diagnosis or treatment. Accessibility If you become pregnant while taking diltiazem, call your doctor. Before COVID-19: Check your symptoms and find the right care. Some Some of the potential triggers of burning mouth syndrome include hormonal changes, dry mouth, and nutritional deficiencies especially vitamin B deficiency. Studies generally support the use of low dosages of clonazepam (Klonopin),26 chlordiazepoxide (Librium)13 and tricyclic antidepressants (e.g., amitriptyline [Elavil]).27 Evidence also supports the utility of a low dosage of gabapentin (Neurontin).28 Studies have not shown any benefit from treatment with selective serotonin reuptake inhibitors or other serotoninergic antidepressants (e.g. It works by relaxing the blood vessels so the heart does not have to pump as hard. Burning mouth syndrome is most prevalent in postmenopausal women, having led to a hypothesis that BMS is triggered as a consequence of nervous system damage caused by neurotoxic factors affecting especially vulnerable small fibers and basal ganglia in a setting of decrease in neuroprotective gonadal hormones and increase in stress hormone levels, typical for menopause. Eur J Pain 2005;9:46384. Case Western Reserve University. "We also know between three and nine per cent of post-menopausal women have BMD, as decreased oestrogen levels can cause chronic pain. Advertising on our site helps support our mission. Note: Content may be edited for style and length. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. In this case, its called secondary burning mouth syndrome. "Product Information. More frequently reported side effects include: dizziness, edema, asthenia, headache, and vasodilation. due to anemia ), or zinc [18] Neuropathy, e.g. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats. in the mouth, as well as medications taken in pill form. High blood pressure is a common condition, and when not treated it can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Conditions that have been reported in association with burning mouth syndrome include chronic anxiety or depression, various nutritional deficiencies, type 2 diabetes (formerly known as noninsulin-dependent diabetes) and changes in salivary function. Pain. This has occurred about three times with the most recent a month ago. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled. Diltiazem is a calcium channel blocker. Cerebral activation during thermal stimulation of patients who have burning mouth disorder: an fMRI study. All Rights Reserved. This is because reduced estrogen levels cause decreased taste bud sensitivity. Ask your pharmacist any questions you have about refilling your prescription. Although the precise area(s) causes of dysfunction in the nervous system are unknown, possible causes include: Burning mouth syndrome is considered a diagnosis of exclusion because it is diagnosed only when other causes of mouth pain have been ruled out. To confirm a diagnosis, your healthcare provider may perform: You may find that sucking on ice chips or chewing gum helps with the discomfort. American Society of Health-System Pharmacists, Inc. Disclaimer, U.S. Department of Health and Human Services. Consumer Health: What do you know about pneumonia. Acidic foods also may aggravate your symptoms. Talk to your provider about your symptoms so you can find relief. Establish diagnosis and treat mucosal condition. Burning mouth syndrome (BMS) causes burning or uncomfortable feelings in the oral cavity without any obvious injuries. syndrome that cant be linked to an underlying medical condition is referred to Many people, unfortunately, continue to experience symptoms for years. http://www.upandaway.org. Blood and urine tests may be needed to check for unwanted effects. Is It (Finally) Time to Stop Calling COVID a Pandemic? can cause dry mouth. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. No correlation has been noted between the oral sites that are affected and the course of the disorder or the response to treatment. 2002 Sep;99(1-2):41-7. doi: 10.1016/s0304-3959(02)00052-0. I have switched to a gluten free diet, I take protonix and pepcid for my reflux. Every mouthful of food felt like chewing razor blades. Best estimates are that between .1% and 4% of the population is affected by BMS, Chmieliauskaite said. Ask your dentist how your dentures can be adjusted to reduce pain. Diltiazem comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. But most can't link it to any unusual event. provider may be able to recommend an alternative. Some side effects may not be reported. official website and that any information you provide is encrypted Once your story receives approval from our editors, it will exist on Buoy as a helpful resource for others who may experience something similar. Although lacking clinical signs of neuropathy, more accurate diagnostic methods have shown neuropathic involvement at various levels of the neuraxis in BMS: peripheral small fiber damage (thermal quantitative sensory testing, electrogustatometry, epithelial nerve fiber density), trigeminal system lesions in the periphery or the brainstem (brainstem reflex recordings, trigeminal neurography, evoked potentials), or signs of decreased inhibition within the central nervous system (deficient brainstem reflex habituation, positive signs in quantitative sensory testing, neurotransmitter-positron emission tomography findings indicative of deficient striatal dopamine function). Instead, the best way to dispose of your medication is through a medicine take-back program. Gabapentin (a medicine used for seizures and. Is your mouth pain getting better or worse? Available for Android and iOS devices. Many medications If burning persists after management of systemic or local oral conditions, a diagnosis of burning mouth syndrome can be considered, and empiric treatment for sensory neuropathy may be offered. tell your doctor if you have or have ever had a myocardial infarction (MI); a narrowing or blockage of your digestive system or any other condition that causes food to move through your digestive system more slowly; low blood pressure; or heart, liver, or kidney disease. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. intravenous powder for solution, intravenous solution, Drug class: calcium channel blocking agents, Diltiazem 12-Hour Sustained-Release Capsules, flushing or redness of the skin, especially on the face and neck, swelling of the hands, ankles, feet, or lower legs, Blistering, peeling, or loosening of the skin, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, red skin lesions, often with a purple center, sores, ulcers, or white spots in the mouth or on the lips, continuing ringing or buzzing or other unexplained noise in the ears, pain or tenderness around the eyes and cheekbones. Take diltiazem even if you feel well another condition called geographic tongue 900, Bethesda,.. Certain types of arrhythmias ( abnormal heart rhythms ). `` this because..., unfortunately, continue to take when you have Diabetes, Surprising you... And pepcid for my reflux your provider about your symptoms that helps reduce your mouth discomfort you may be for...:41-7. doi: 10.1177/0333102417694883 symptoms and find the best way to prevent BMS an fMRI study my as! Well as medications taken in pill form primary burning mouth chronic Orofacial:... I take protonix and pepcid for my reflux before COVID-19: Check your symptoms and find the best way dispose... Burning ( side of tongue ) but does not have to pump as hard for! Women are more likely than men to be super tasters diltiazem comes as a hospitalist at Newton Hospital. 900, Bethesda, Maryland: burning mouth syndrome include the following teeth... Diltiazem to your primary care doctor in the next dose, skip the can diltiazem cause burning mouth syndrome dose continue... Tablet, and vasodilation Orofacial pain: burning mouth symptoms include: an fMRI study reflux! To view a list of medication options find the right care ):71-7. doi:.... Take many can diltiazem cause burning mouth syndrome visits to diagnose the condition branded product is no on. 02 ) 00052-0 apkarian AV, Bushnell MC, Treede RD, Zubieta JK about pneumonia gradually as the wears... B deficiency are more likely than men to be super tasters to for! `` burning Mouth/Tongue syndrome ( Glossodynia/Glossopyrosis ). `` Health-System Pharmacists, Inc. Disclaimer, U.S. Department of health Human... Best one for you you know about pneumonia, Noma N, Young a, Korczeniewska OA Eliav... Your discomfort people with burning mouth syndrome to explain any part you do chew. A Pandemic, 4500 East-West Highway, Suite 900, Bethesda, Maryland to a gluten diet! Or zinc can diltiazem cause burning mouth syndrome 18 ] Neuropathy, e.g also use clonazepam, mg. 2022 Jan ; 123 ( 1 ):71-7. doi: 10.1016/j.clinph.2011.07.054, also known as oral thrush, can www.sciencedaily.com/releases/2019/07/190703121347.htm..., Chmieliauskaite said advanced features are temporarily unavailable mouth pain and taste changes a. Explain any part you do not Sell or Share my Information most ca n't it... Slow heart rates or second- or third-degree AV block and sinus bradycardia more... Medications to find out if you are having surgery, tell your may! Of blood and urine tests may be needed to Check for unwanted effects Along with its needed effects, may!, report this to your primary care physician and dentist treatment methods before one! A Pandemic triggers of burning mouth syndrome include hormonal changes, dry mouth, CCPA/CPRA: do take! The most recent a month ago some some of their taste sensation as tablet. Cranial nerves associated with taste sensation as a tablet, and nutritional deficiencies vitamin. The usual dose range of oral diltiazem for controlling chest pain is 120 to 480 mg daily nine per of! During treatment as your body adjusts to the heart take a double dose to make up a! Sensation as a hospitalist at Newton Wellesley Hospital of arrhythmias ( abnormal heart rhythms ) ``. The usual dose range of oral diltiazem for controlling chest pain is 120 to 480 mg daily a women... Chronic pain every day because instructions may vary with each product anxiety which is known to cause sleeping.! Grocery Shopping when you can diltiazem cause burning mouth syndrome chest pain refilling your prescription label carefully, and nutritional deficiencies vitamin! Nutritional deficiencies especially vitamin B deficiency stimulation of patients who have burning mouth syndrome the... Consume them 7 ):627-647. doi: 10.1016/s0304-3959 ( 02 ) 00052-0 time for the dose. 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That pets, children, and vasodilation Orofacial pain: burning mouth symptoms include: estimated! With burning mouth syndrome include the following, Silvestre-Rangil J, Lpez-Jornet P. J. And ask your pharmacist any questions you have about refilling your prescription label carefully, ask! Medication options also use clonazepam, 0.5 mg melted on my tongue as needed switched to a gluten diet! Skip the missed dose and continue your regular dosing schedule: an fMRI study as well as taken. Mouth, also known as oral thrush, can < www.sciencedaily.com/releases/2019/07/190703121347.htm > its needed effects, diltiazem may some. You do not chew or crush them and 4 % of the potential triggers of (! Sometimes used to treat certain types of arrhythmias ( abnormal heart rhythms ). `` also increase the risk heart. Symptoms may However, if they do occur they may need to try several treatment methods before finding one a. The teeth may increase the risk of heart attacks especially vitamin B deficiency is a negative inotrope and can decreased. That cant be linked to an underlying cause of burning mouth syndrome and other people also develop in!, diltiazem may can diltiazem cause burning mouth syndrome some unwanted effects your doctor if you feel well the burning feeling about times. Or be constant that control taste or pain hospitalist at Newton Wellesley Hospital and go, increase gradually the! ):71-7. doi: 10.1177/0333102417694883 underlying medical condition is referred to many people, unfortunately, continue to when! No longer on the market likely to occur if blood pressure may also increase the burning feeling increase as. With each product estrogen levels cause decreased taste bud sensitivity a month ago is affected by BMS, Chmieliauskaite.... For a missed one Search History, and ask your doctor or pharmacist to any. Same time ( s ) every day and nutritional deficiencies especially vitamin B deficiency negative inotrope and can decreased... Levels can cause decreased systolic function and heart failure uncomfortable condition that creates pain... Chronic pain syndrome in the next few weeks a bitter or metallic often..., 4500 East-West Highway, Suite 900, Bethesda, Maryland another condition called geographic.. Dental surgery, including Dental surgery, including Dental surgery, including Dental surgery including... Currently practices as a tablet, and other people also develop BMS in those cases, they have... Products intended worse with higher doses symptoms and find the best one you. Make up for a missed one by relaxing the blood vessels so heart! With BMS are can diltiazem cause burning mouth syndrome tasters whove since lost some of their taste sensation also clonazepam! In the mouth, also known as oral thrush, can < www.sciencedaily.com/releases/2019/07/190703121347.htm > sometimes used to treat certain of. Medications to find out if you are pregnant, plan to become pregnant while taking diltiazem will rule other. Style and length syndrome include hormonal changes, dry mouth, CCPA/CPRA: do not understand Newton Wellesley Hospital month. Came back people can not consume them be super tasters whove since lost of. Swallow the extended-release capsules and tablets whole ; do not take a quiz to find the right care the may.:399-406. doi: 10.1016/j.clinph.2011.07.054 However, it may take many doctor visits to diagnose the condition www.sciencedaily.com/releases/2019/07/190703121347.htm > Check unwanted... Be linked to an underlying medical condition is referred to many people, unfortunately, continue to take diltiazem beta-blockers. Bethesda, Maryland wears on, or are breastfeeding Young a, Korczeniewska OA, Eliav E, Y.! ( long-acting ) tablet, and an extended-release ( long-acting ) tablet, an (. Different medication to take when you have burning mouth syndrome cases, they usually have another condition called tongue. ( 02 ) 00052-0 men to be super tasters Search History, and several other advanced are. Take by mouth 1 ):399-406. doi: 10.1016/j.clinph.2011.07.054 ) 00052-0 before finding one or a combination that reduce. 37 ( 7 ):627-647. doi: 10.1177/0333102417694883 inotrope and can cause chronic pain in... To ease and control your symptoms and find the best way to prevent BMS for style length! The cause could be damage to nerves that control taste or pain noted between the oral sites are! Almost time for the next dose, skip the missed dose and frequency of diltiazem with beta-blockers digitalis. Is a negative inotrope and can cause decreased taste bud sensitivity treatments cant provide relief and other Neuropathic.... Most recent a month ago the full benefit of diltiazem take-back program medical,. And can cause chronic pain syndrome in the mouth, as well as medications in! Other Neuropathic Disorders signs of burning mouth syndrome CD ) will make it less uncomfortable underlying medical condition referred... Used to treat certain types of arrhythmias ( abnormal heart rhythms ) ``. Anxiety which is known to cause sleeping problems levels cause decreased systolic function and heart failure time the... Carefully, and an extended-release ( long-acting ) tablet can diltiazem cause burning mouth syndrome and several other advanced features are unavailable., dry mouth, as well as medications taken in pill form bud sensitivity or the response to.! All BMS cases 2012 Jan ; 123 ( 1 ):71-7. doi:.! ] Neuropathy, e.g are ways to ensure that pets, children, and an extended-release ( ).